• Express o territorial desta expans o

  2019-06-28

  

  Expressão territorial desta expansão, no início dos anos 1990 as concessões mineiras ocupavam 2.3 milhões de hectares, enquanto na atualidade, beiram 25 milhões. A atividade deixou de se concentrar nas alturas andinas expandindo‐se para os vales, cell culture supplement costa e inclusive a Amazônia.

• br Conflict of interest br

  2019-06-28

  

  Conflict of interest Introduction Garrigue et al. reported that atrial overdrive pacing reduces the number of sleep AT-406 episodes in pacemaker patients without heart failure [1]. However, this finding has not been replicated in subsequent investigations [2–5], although some meta-analysis st

• LQTS is classified into subtypes LQT to LQT

  2019-06-28

  

  LQTS is classified into subtypes LQT1 to LQT13 based on the site of genetic mutation. Each type possesses distinct clinical characteristics and a different prognosis. Treatment choice depends partly on individual phenotype and partly on genotype. Among Asian countries, several reports have been publ

• Eligio Mar a Ancona Castillo

  2019-06-28

  

  Eligio María Ancona Castillo nació en la ciudad de Mérida, el 1° de diciembre de 1836. Después de cursar los estudios elementales en la escuela de su padre, inició los cursos preparatorios en el Seminario Conciliar de San Ildefonso. Más tarde se inscribió en la Universidad del Estado para iniciar la

• br The follow up clinic These trial

  2019-06-27

  

  The follow-up clinic These trial results have significant implications for clinic efficiencies. The safe and effective replacement of the bulk of “routine” in-clinic evaluations demonstrated in TRUST (Fig. 3) has a huge implication for resource utilization. Although demanding adjustment to diffe

• Letsas et al reported that

  2019-06-27

  

  Letsas et al. reported that the prevalence of Brugada-type ECG was 0.34% in men and 0.04% in women in the Greek population [19]. Despite the similar BS gender differences between the Greeks and the Japanese, many multicenter studies performed in Western countries indicated that the frequency of men

• Involvement of the ventricular myocardium can lead to delaye

  2019-06-27

  

  Involvement of the ventricular myocardium can lead to delayed conduction or anatomical obstacles that are labile to ventricular tachyarrhythmia. Arrhythmias are independently predictive of sudden cardiac death (SCD) [9]. SCD is common in patients with cardiac AL amyloidosis, and prophylactic implant

• gsk-3 After the RFCA neither sustained VT nor the VPCs that

  2019-06-27

  

  After the RFCA, neither sustained VT nor the VPCs that triggered the VT were recorded. The patient was fitted with a WCD (LifeVest, Zoll, Pittsburgh, PA, USA) on the third day post-ablation, and sotalol 80mg a day was started. He was discharged from the coronary care unit the following day. During c

• br Materials and methods br

  2019-06-27

  

  Materials and methods Results and discussion ABT-737 is a BH3-mimetic targeting Bcl-2, Bcl-XL and Bcl-W. The aim of the experiments was to test whether inhibition of Bcl-2 and Bcl-XL using ABT-737 can eradicate the CD34+/CD38− AML cell population. Bone marrow MNCs from patients (Table 1) were

• Based on the close relationship of the canine wedge model

  2019-06-27

  

  Based on the close relationship of the canine wedge model to human ECGs, individuals with prominent J waves (ERS) or J/ST elevation (BS) are thought to have accentuated ventricular AP notch and the potential to lose their AP dome because of extrinsic factors such as vagal stimulation, sodium channel

• Adhesive interactions Adhesive interactions between myeloma

  2019-06-27

  

  Adhesive interactions: Adhesive interactions between myeloma Meropenem trihydrate structure and stromal cells play a significant role in both the homing of MM cells to the bone marrow and augmentation of the bone destructive process. These adhesive interactions result in activation of NF-κB and p38

• br Future directions There is

  2019-06-27

  

  Future directions There is increasing evidence that osteoblasts are important components of the bone metastatic niche, but their precise contribution in supporting tumour cell engraftment, dormancy and survival remains to be defined. Unlike osteoclasts, the role of osteoblasts in bone metastasis

• br Discussion and outstanding questions Reproductive endocri

  2019-06-27

  

  Discussion and outstanding questions Reproductive endocrine hormones such as inhibin affect breast cancer cell survival in the primary tumour and affect tumour homing and survival in the bone microenvironment. The molecular mechanism driving this effect of hormones in bone is likely to be multifa

• br Therapy for the CPVT br Conflict of interest

  2019-06-27

  

  Therapy for the CPVT Conflict of interest Acknowledgment This work was supported by Health Science Research grant from the Ministry of Health, Labour and Welfare of Japan for Clinical Research on Measures for Intractable Diseases (2016-032). Introduction Bradyarrhythmia is a serious ele

• Cerrone et al reported that

  2019-06-27

  

  Cerrone et al. reported that the mechanism of CPVT was due to delayed afterdepolarization‐induced triggered activity in a focal Purkinje network in a knock-in (RyR2) mouse [36]. In addition, chemical ablation of the RV endocardial cavity with Lugol׳s solution, which selectively destroys the Purkinje

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