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br The follow up clinic These trial
2019-06-27

The follow-up clinic These trial results have significant implications for clinic efficiencies. The safe and effective replacement of the bulk of “routine” in-clinic evaluations demonstrated in TRUST (Fig. 3) has a huge implication for resource utilization. Although demanding adjustment to diffe
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Letsas et al reported that
2019-06-27

Letsas et al. reported that the prevalence of Brugada-type ECG was 0.34% in men and 0.04% in women in the Greek population [19]. Despite the similar BS gender differences between the Greeks and the Japanese, many multicenter studies performed in Western countries indicated that the frequency of men
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Involvement of the ventricular myocardium can lead to delaye
2019-06-27

Involvement of the ventricular myocardium can lead to delayed conduction or anatomical obstacles that are labile to ventricular tachyarrhythmia. Arrhythmias are independently predictive of sudden cardiac death (SCD) [9]. SCD is common in patients with cardiac AL amyloidosis, and prophylactic implant
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gsk-3 After the RFCA neither sustained VT nor the VPCs that
2019-06-27

After the RFCA, neither sustained VT nor the VPCs that triggered the VT were recorded. The patient was fitted with a WCD (LifeVest, Zoll, Pittsburgh, PA, USA) on the third day post-ablation, and sotalol 80mg a day was started. He was discharged from the coronary care unit the following day. During c
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br Materials and methods br
2019-06-27

Materials and methods Results and discussion ABT-737 is a BH3-mimetic targeting Bcl-2, Bcl-XL and Bcl-W. The aim of the experiments was to test whether inhibition of Bcl-2 and Bcl-XL using ABT-737 can eradicate the CD34+/CD38− AML cell population. Bone marrow MNCs from patients (Table 1) were
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Based on the close relationship of the canine wedge model
2019-06-27

Based on the close relationship of the canine wedge model to human ECGs, individuals with prominent J waves (ERS) or J/ST elevation (BS) are thought to have accentuated ventricular AP notch and the potential to lose their AP dome because of extrinsic factors such as vagal stimulation, sodium channel
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Adhesive interactions Adhesive interactions between myeloma
2019-06-27

Adhesive interactions: Adhesive interactions between myeloma Meropenem trihydrate structure and stromal cells play a significant role in both the homing of MM cells to the bone marrow and augmentation of the bone destructive process. These adhesive interactions result in activation of NF-κB and p38
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br Future directions There is
2019-06-27

Future directions There is increasing evidence that osteoblasts are important components of the bone metastatic niche, but their precise contribution in supporting tumour cell engraftment, dormancy and survival remains to be defined. Unlike osteoclasts, the role of osteoblasts in bone metastasis
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br Discussion and outstanding questions Reproductive endocri
2019-06-27

Discussion and outstanding questions Reproductive endocrine hormones such as inhibin affect breast cancer cell survival in the primary tumour and affect tumour homing and survival in the bone microenvironment. The molecular mechanism driving this effect of hormones in bone is likely to be multifa
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br Therapy for the CPVT br Conflict of interest
2019-06-27

Therapy for the CPVT Conflict of interest Acknowledgment This work was supported by Health Science Research grant from the Ministry of Health, Labour and Welfare of Japan for Clinical Research on Measures for Intractable Diseases (2016-032). Introduction Bradyarrhythmia is a serious ele
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Cerrone et al reported that
2019-06-27

Cerrone et al. reported that the mechanism of CPVT was due to delayed afterdepolarization‐induced triggered activity in a focal Purkinje network in a knock-in (RyR2) mouse [36]. In addition, chemical ablation of the RV endocardial cavity with Lugol׳s solution, which selectively destroys the Purkinje
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br The estimated number of
2019-06-27

The estimated number of women who die each year from causes related to pregnancy or childbirth has dropped substantially—from 543 000 deaths in 1990 to about 287 000 in 2010. Nevertheless, maternal mortality ratios remain among the least equitable of all health indicators, ranging from less than f
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Magall n es muy claro al decir que la
2019-06-27

Magallón es muy claro al decir que la aplicación de las políticas neoliberales en América Latina no significaron cohesión social ni la apropiación de la idea “necesaria” de humanidad. “El mayor problema de estos países sigue siendo la pobreza, la desigualdad social y de oportunidades, la desigualdad
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Menci n aparte merecen dos
2019-06-27

Mención aparte merecen dos rasgos en la construcción de este personaje y de su entorno: en primer lugar, sufre de una úlcera en el duodeno que lo hace beber leche en múltiples momentos o mitigar el dolor masticando antiácidos Pepsamar. Mattos se está consumiendo por dentro, en una metáfora que utili
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br Drug resistance In clinical
2019-06-27

Drug resistance In clinical practice, there is no cross–drug-resistance between As2O3 and RA or other antileukemic agents. This may be explained by the non-liposoluble nature of As2O3, its small molecular weight, and its distinctive modes of action [20]. In our observation, primary As2O3 resistan
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