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The concept of personalised medicine is not new however
2018-11-13
The concept of personalised medicine is not new, however the rapid advances in technologies such as genomics, transcriptomics and metabolomics for the analysis of blood and tissue has opened up new horizons in this area in the last few years (). As outlined above, the range of biotherapeutics now av
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glp-2 To investigate this potentially increased proportion
2018-11-13
To investigate this potentially increased proportion of patients with rapid progression to AIDS over the last decade in Cuba, we set up an exploratory study evaluating the association of rapid progression with epidemiological, clinical, viral and immunological parameters, comparing three groups of p
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As a result the gp
2018-11-13
As a result, the gp120 V1V2 region has been of intense interest owing to its immunogenic promise; however, V1V2 has proven difficult to characterize structurally. V1V2 has been observed in crystal structures in a variety of conformations. Bound to GSK503 CH58 and CH59 isolated from RV144 vaccinees,
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flap inhibitor Due to their buoyancy circulating
2018-11-13
Due to their buoyancy, circulating tumor flap inhibitor (CTCs) are found in the white blood cell fraction. CTCs have been investigated as a non-radiographic tool to monitor disease progression. The presence of CTCs suggests increased metastatic potential, and they have been investigated as a predic
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If KIT mutations are to
2018-11-12
If KIT mutations are to be used as markers to select melanoma patients for imatinib treatment, there is no doubt that tumor specimens should be subjected to mutational analysis. However, practical problems will be encountered when equipment (such as an FDA-approved DNA sequencer) is not available or
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However the use of friction surfacing process for many appli
2018-11-12
However, the use of friction surfacing process for many applications has been limited due to the difficulty of monitoring and control of the process outputs, such as bond quality and coating dimensions [4]. Proper selection of process parameters is vital for obtaining the quality coatings using fric
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br Validation of PVIED The validation was done with
2018-11-12
Validation of PVIED The validation was done with experiments that used the small generic vehicles presented in Chapter 2. Two different vehicle designs were chosen: one with a flat floor and the second with a V-shaped floor. In the actual burial configuration, a high explosive mass of 200 g in a
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The parameter shows how the sliding of the plate
2018-11-12
The δ-parameter shows how the sliding of the plate along the projectile influences the tendency of projectile fragmentation. However the δ-parameter as suggested in Ref. [4] is dependent on the geometric scale and the influence of the lateral stress was not considered. In order to improve the model,
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Joshi et al have reported
2018-11-12
Joshi et al. [8] have reported effect of different welding techniques and external heat extraction methods on heat affected zone softening in dissimilar metal weld joints of maraging steel and AISI 4130 steel. They used continuous current and pulsed current modes in TIG and applied an external water
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Primary stability can be measured by different
2018-11-12
Primary stability can be measured by different methods [14]: “biomechanical tests, including purchase pppa and disinsertion torque measurements, and non-invasive techniques such as resonance frequency analysis (RFA)”. RFA offers a clinical measure for implant stability and presumed osseointegration
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br Conceptual model building The conceptual model
2018-11-12
Conceptual model building The conceptual model for this study is built on the theoretical grounding of Social Network theory, Trust Transfer theory, and Task-Technology Fit theory. Extensive review of the literature resulted in the identification of six constructs i.e. informational support, at l
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Taken this recommendation into account the criterion of whic
2018-11-12
Taken this cannabinoid receptor recommendation into account, the criterion of which the difference between simulation (E [lx]) and measurement (E [lx]) values do not lead to a significant difference in their subjective effect isIn other words, the ratio of simulation and measurement values at any m
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Compared with the dichotomy between the authenticity
2018-11-12
Compared with the dichotomy between the authenticity of the avant-garde and fake kitsch in Greenberg, antagonism toward the public and the past in Poggioli, and the understanding of the avant-garde as a face of modernity in Calinescu, Peter Bürger takes a historical approach to review the developme
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Although there are proper courtyards behind the bedrooms
2018-11-12
Although there are proper courtyards behind the bedrooms in Can Lis, they are used for security and necessity. Can Feliz, with its raised Chinese “fire protection” gable walls, pitched roofs, and the embracing gesture towards the semi-enclosed centre, nearly wants to be a Chinese house. The rooms st
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An inverted papilloma is a primary
2018-11-12
An inverted papilloma is a primary benign epithelial tumor of the nose and paranasal sinus. It is uncommon in the general population; however, inverted papillomas account for 0.5–5% of primary nasal tumors. An inverted papilloma of the sphenoid sinus occurring in correlation with precipitating fact
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