• Introduction Raw water in South Africa is considered

  2018-11-05

  

  Introduction Raw water in South Africa is considered a strategic national resource, with the responsibility for its management taking place at three tiers. These are firstly Central Government, secondly Provincial and Regional Governments, including other specified authorities, and thirdly Local Au

• Several new mutations in the NPC NPC and SMPD

  2018-11-05

  

  Several new mutations in the NPC1, NPC2 and SMPD1 genes were found in this study. All these mutations are predicted to be disease causing (online program “mutation taster” Schwarz et al., 2014) except for the splice mutation IVS4+1G>A in NPC2, which is a known variant (rs140130028). Only heterozygot

• We also revealed that Scd is a functional

  2018-11-05

  

  We also revealed that Scd1 is a functional target of miR-378 that promotes lipolysis in adipose tissues of miR-378 Tg mice. SCD1 critically regulates lipid metabolism, and dysregulation of SCD1 activity results in various metabolic disorders, including diabetes, cardiovascular disease, and obesity (

• In this issue of EBioMedicine push

  2018-11-05

  

  In this issue of EBioMedicine, push this topic in a new direction in their study of men who have sex with men (MSM) and others in Barcelona and Stockholm. Their participants, 129 HIV-positives (60% MSM) and 27 HIV-negatives (85% MSM) in Barcelona, and 77 HIV-positives (25% MSM) and 7 HIV-negatives

• In this study we modeled

  2018-11-05

  

  In this study, we modeled VC to project DEP in Europe given changes in climate. Throughout this study, we have included DTR in all of our VC calculations. We expanded our previous relative VC model to VC, by including temperature dependent dynamics in the female vector-to-human population ratio (Liu

• In their manuscript in Psomas

  2018-11-05

  

  In their manuscript in , Psomas and colleagues used a combination of 68 markers of immune activation and inflammation and two independent hierarchical clustering analyses to identify 5 donor groups from among 120 HIV-infected virologic responders (). These donor groups were characterized using combi

• br Materials Methods br Results To better understand how ZIK

  2018-11-05

  

  Materials & Methods Results To better understand how ZIKV infection may lead to microcephaly, we developed an assay to infect cultured mouse embryonic order ON-01910 slices and tested the ability of ZIKV and other flaviviruses to infect the neocortex (Fig. 1a). We selected an isolate of DENV

• To prevent the negative impact of hemolysis the

  2018-11-05

  

  To prevent the negative impact of hemolysis, the U.S. Food and Drug Administration set the upper threshold of hemolysis in a RBC unit to be transfused at 1% but some RBC units stored under standard blood banking conditions fail to meet this requirement due to factors that may be donor specific (Mish

• Disclosure br Foxp regulatory T Treg cells

  2018-11-05

  

  Disclosure Foxp3 regulatory T (Treg) Ki16425 are known to restrict anti-tumor immune responses and promote tumor progression (). Therapeutic utility of attenuating Treg cell function is one of the most exciting developments in the current field of tumor immunology. Temporary release from the sup

• At present of hydrogen is produced directly from fossil fuel

  2018-11-05

  

  At present, 96% of hydrogen is produced directly from fossil fuels and only about 4% is produced by the use of renewable resources that are carbon free (Abdollahi et al., 2012). The production of hydrogen is expected to increase in the future as the world moves toward the greater use of hydrogen as

• Furthermore an independent association between SOS

  2018-11-05

  

  Furthermore, an independent association between SOS episodes and sleep disturbances such as RBD symptoms was observed. Cumulative evidence shows that RBD precedes the development of PD by many years [24–26]. Previously, a reduction of median cerebellar peduncle that carries key structures from the r

• The studies that were described emphasize the

  2018-11-05

  

  The studies that were described emphasize the presence of a-MCI and DA. But when we talk about MCI and sleep disorders, there is another group which must be cited. Rapid eye movement (REM) sleep behavior disorder (RBD) is a form of parasomnia characterized by the presence of abnormal and often viole

• EPISONO is an epidemiological sleep study that

  2018-11-05

  

  EPISONO is an epidemiological sleep study that was performed with a sample representing the São Paulo population in 2007. All volunteers were submitted to a single night polysomnography on sleep laboratory and to complete questionnaires before and after exam, one of these questionnaire was about SB

• Doxorubicin DOXO a member of the

  2018-11-05

  

  Doxorubicin (DOXO), a member of the antineoplastic antibiotic family of anthracyclines, is a chemotherapeutic agent developed in the 1960s [5], that is still widely used in the treatment of a variety of malignancies, such as acute leukemia, non-Hodgkin lymphomas, breast cancer, Hodgkin\'s disease, a

• Introduction In mammals the suprachiasmatic nucleus

  2018-11-05

  

  Introduction In mammals, the suprachiasmatic nucleus (SCN) of the anterior hypothalamus is the master oscillator that controls circadian output [1,2]. The circadian information from environmental light/dark Purmorphamine cost is received via the retinohypothalamic tract, and thus, the phase of the

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