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The mechanisms of abdominal blunt trauma that cause
2018-10-29

The mechanisms of abdominal blunt trauma, that cause intestinal perforation in the hernia sac, have received various explanations. Reynolds asserted that direct trauma to an inguinal hernia can produce enough pressure to cause perforation of the intestinal walls. A study by O’Leary and MacGregor sho
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Introduction Lumbar zygapophysial or facet
2018-10-29

Introduction Lumbar zygapophysial or facet joint pain has been suggested to be an important cause of chronic low back pain. Lumbar medial branch blocks are used to test if a patient\'s pain stems from a given lumbar facet joint. The diagnosis of facet joint pain is probable when there is at least 5
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br Conclusion br Acknowledgments This project
2018-10-29

Conclusion Acknowledgments This project was supported by the KMUH98-8R22 grant. Introduction Carpal tunnel syndrome (CTS) is the most common glucokinase neuropathy of the upper extremity, and it accounts for 90% of all entrapment neuropathies. The typical symptoms of CTS include paresthes
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The endotracheal tube was removed and the
2018-10-29

The endotracheal tube was removed and the patient was transferred to a ward on the 4th postoperative day. The postoperative course was unremarkable. A pus culture was positive for Escherichia coli. The patient was discharged in a stable condition on the 14th day after the operation. Discussion A
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Damascenone Fig and ionone Fig a are two representative arom
2018-10-29

β-Damascenone (Fig. 3) and β-ionone (Fig. 4a) are two representative aromas formed from carotenoid degradation. β-damascenone has an apple-like flavor and has an extremely low threshold in water (0.002ppb). It was first identified in Bulgarian rose oil in 1970 [9] and is an essential odor in black t
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The scavenging abilities of compound and fractions on hydrog
2018-10-29

The scavenging abilities of compound 1 and fractions 2–6 on hydrogen peroxide need to be evaluated (Table 2) because even though it is not very reactive in human cells, hydrogen peroxide sometimes is toxic because it gives rise to the hydroxyl radical in cells [41]. Thus, antioxidants that remove hy
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In addition to abnormal expression of cell cycle
2018-10-29

In addition to abnormal expression of mitotic inhibitors genes, an irregular expression of genes involved in DNA break repair such as APEX, XRCC4 and XRCC6 was observed with the progression of age. Age associated downregulation of APEX has been shown in male germ line cells (Allen et al., 2008). Sim
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Gregg and Weiss demonstrated that intraventricular injection
2018-10-29

Gregg and Weiss (2003) demonstrated that intraventricular injection of EGF and TGF-α induces the generation of RGLCs in the SVZ in adult mice. Zhou et al. (2001) demonstrated that TGF-α induces, in vitro, the differentiation of mature astrocytes into radial cells. We analyzed the levels of TGF-α mRN
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gpr55 agonist We conclude that most CD intLin SCA
2018-10-29

We conclude that most CD45−/intLin−SCA-1+ gpr55 agonist in mouse BM were not as small as previously reported. Moreover, even despite broadening our search to include larger cells as candidates, we could not find a single instance of CD45−/intLin−SCA-1+ cells that (1) expressed Oct4, (2) proliferate
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Cell surface markers that have proved
2018-10-29

Cell surface markers that have proved useful for the isolation of mouse PAX7+ satellite (-)-JQ1 include ITGA7 (Pasut et al., 2012; Sacco et al., 2008), CXCR4 and β1 INTEGRIN (Sherwood et al., 2004), and VCAM1 (Chakkalakal et al., 2012). Our studies indicate that PAX7-expressing cells in fetal and a
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The advent of new technologies such as
2018-10-26

The advent of new technologies such as TALENs and CRISPRs offer extremely powerful methods for enhanced gene editing (Gaj et al., 2013). Indeed, these technologies have been shown to target the AAVS1 locus with similar efficiencies as ZFNs (Hockemeyer et al., 2011; Mali et al., 2013). However, targe
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The negative regulation of Zac expression by SOXB transcript
2018-10-26

The negative regulation of Zac1 expression by SOXB1 transcription factors combined with the decrease of Sox2 expression as the levels of Zac1 increase suggest that ZAC1 and SOXB1 factors could act as a cross-repressive genetic switch governing the acquisition of distinct cellular identities (Enver e
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nevertheless br Results br Discussion In
2018-10-26

Results Discussion In this study we provide several lines of evidence that Dnd serves as a critical PGC specifier in medaka. First, dnd knockdown is capable of specifically and completely abolishing PGC formation and its overexpression is sufficiently capable of inducing ectopic PGCs in embryo
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cathepsin inhibitor Study of microglia has been largely rest
2018-10-26

Study of microglia has been largely restricted to non-human models (mostly mouse), since availability of fresh primary human microglia is very limited and they cannot be propagated. Moreover, microglia rapidly lose their unique identity when removed from the cathepsin inhibitor environment and cultu
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Background In recent years there has been growing attention
2018-10-26

Background In recent years, there has been growing attention paid by researchers, land-use planners and policymakers to the number and types of food stores within neighbourhoods (Caspi, Sorensen, Subramanian & Kawachi, 2012; Fraser, Edwards, Cade & Clarke, 2010; Kent & Thompson, 2014; Ni Mhurchu e
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