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The use of FTAI can overcome the negative impact of
2024-10-22
The use of FTAI can overcome the negative impact of low estrus detection efficiency, but implies effective synchrony of luteal function as well as synchronous growth and ovulation of a viable Q-VD Oph synthesis follicle. Pregnancy rates obtained with FTAI may be comparable or better than those obta
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(-)-Huperzine A receptor As a neuropeptide Apelin also has a
2024-10-22
As a neuropeptide, Apelin also has a critical role in cardiovascular diseases. Systemic administration of Apelin exert vasodilatory and antihypertensive effects [33]. Meanwhile, the apelin-APJ signal transduction pathway is related to age-associated cardiovascular diseases [34]. It has been known th
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Agarose GPG/ME australia Plant defensins are cysteine rich c
2024-10-22
Plant defensins are cysteine-rich cationic peptides of 5–8 kDa whose mature domain comprises 45 to 54 amino Agarose GPG/ME australia residues, with an isoelectric point around 9. The global fold of plant defensins consists of a cysteine-stabilized motif (CSα/β) made up of an α-helix and a triple-str
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The diversity of metabolic adaptations employed
2024-10-22
The diversity of metabolic adaptations employed by cancer cells in response to rapidly changing conditions, contributes to their biological aggressiveness and therapeutic resistance by enabling them to proliferate when nutrients are plentiful and to shift their resources to survival when nutrients a
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Adenosine receptors activate a number
2024-10-22
Adenosine receptors activate a number of signalling pathways involved in tissue survival including several mitogen-activated protein kinases (Fredholm et al., 2001). The common feature of all adenosine receptors is the positive coupling to ERK1/2, whilst A2B and A3 receptors can also activate the st
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Plant material and growth conditions Arabidopsis thaliana ec
2024-10-22
Plant material and growth conditions. Arabidopsis thaliana ecotype Columbia was grown on a mixture of soil, vermiculite, and perlite (4:2:1) with a 16h light/8h dark IT-901 in a temperature-controlled growth room (22°C), unless indicated otherwise. Molecular cloning and plant transformation. The c
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Acetylcholinesterase AChE activity and expression level can
2024-10-22
Acetylcholinesterase (AChE) activity and expression level can be down regulated by TCDD in neuronal cells [3], [6]. Thus AChE could be considered as a target of the neuronal toxicity of dioxin. AChE has several types of transcripts by alternative splicing in the 3′ region of primary transcripts [7],
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br The complementary role of chaperone mediated autophagy Ch
2024-10-21
The complementary role of chaperone mediated autophagy Chaperone-mediated autophagy (CMA) mediates the degradation of specific cellular proteins and participates in the regulation of lipid metabolism, DNA repair, or the response to stress (Kaushik and Cuervo, 2018). CMA provides an alternative pa
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Introduction The MMR system keeps the fidelity
2024-10-21
Introduction The MMR system keeps the fidelity of replication by repairing replication errors such as base-base mispairs and insertions/deletions. It plays a substantial role in restoring the fidelity of DNA and contributing to genome integrity [1]. The components of MMR are conserved in a broad ra
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Phagosomes acquire some hydrolases early during their
2024-10-21
Phagosomes acquire some hydrolases early during their journey from the cell surface to lysosomes. An example for such hydrolase is cathepsin H which is most concentrated in the early phagosome at a pH of approximately 6.3 (Claus et al., 1998), the pH optimum of enzyme activity (Schwartz and Barrett,
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Among steroid saponins ginsenosides are the active
2024-10-21
Among steroid saponins, ginsenosides are the active components of ginseng, a well-known chinese medicinal plant. More than hundreds of different ginsenosides have been isolated from ginseng and have shown in the past to be membrane active substances and to influence the membrane by modulating lipid
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br Removal of therapeutic doses of antibiotics
2024-10-21
Removal of therapeutic doses of (+)-MK 801 from Marek’s Disease Vaccines The impact of this change seems to vary widely among operations, probably dependent on the pre-existing quality of hatching egg production, hatchery sanitation, hatchery management, and brooding management. Increases in 7-d
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Aggregated A species have been
2024-10-21
Aggregated Aβ species have been studied by an array of biophysical techniques, including atomic force microscopy (AFM) [55], transmission electron microscopy (TEM) [56], [57], X-ray diffraction [58], Fourier transform infrared (FTIR) [59], [60], circular dichroism (CD) [61], and nuclear magnetic res
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The role of the adaptive immune response in
2024-10-21
The role of the adaptive immune response in AD is not fully understood and previous studies are controversial. In this context, serum levels of T and B lymphocytes were found to be reduced in AD patients, suggesting a decline of the immune response during the course of the disease (Richartz-Salzburg
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Another possible scenario is that the same pathologic proces
2024-10-21
Another possible scenario is that the same pathologic process has different effects in different people. It might be that the pathway outlined in Fig. 6A is operative in some individuals, but other individuals have a factor Q (which could be genetic or environmental) that blocks the effect of A on T
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