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Zotarolimus br Experimental protocols br Acknowledgements Th
2020-06-13

Experimental protocols Acknowledgements This research was funded by the Croatian Ministry of Science, Education and Sports (Programmes 098-0982915-2948 and 098-0982522-2525), the Austrian Science Fund FWF (DK-MCD W1226, SFB LIPOTOX F30, P22832), and the Croatian-Austrian Intergovernmental S&T
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Semantics play an important role in software component based
2020-06-12

Semantics play an important role in software component-based development as they improve components identification, selection and integration through, among others, the use of ontologies (Kaur and Mishra, 2017). Analogously, they allow to improve discovery, composition and reuse in the context of We
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A robust meta analysis of randomized clinical trials found t
2020-06-12

A robust meta-analysis of 22 randomized clinical trials found that application of ischemic preconditioning strategies reduce ventricular arrhythmias [3]. Additionally, it was demonstrated that remote ischemic perconditioning (perRIC) induces immediate cardioprotection during ongoing ischemia by atte
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br Structural and biochemical features of pol
2020-06-12

Structural and biochemical features of pol X family polymerases The X-family DNA polymerase (polX) is specialized in DNA repair. This family is composed of four different DNA polymerases: pol β, pol λ, pol μ and TdT. Only three members of the polX family possess an N-terminal BRCT (BRCA1 carboxy-
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Phytophthora capsici is a phytopathogenic oomycete a lineage
2020-06-12

Phytophthora capsici is a phytopathogenic oomycete, a lineage of eukaryotic microorganisms in the kingdom Stramenopila, which causes devastating diseases on many economically important vegetables [15]. Hyps are present in the Phytophthora cell wall proteins [16] and phytotoxic elicitor proteins [17]
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Introduction Postoperative delirium POD is
2020-06-12

Introduction Postoperative delirium (POD) is a potentially debilitating disorder experienced by many elderly patients admitted to a surgical intensive care unit (ICU) after noncardiac surgery. Delirium is often defined as acute cognitive dysfunction that is characterized by an altered mental status
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Finally the identification of predictive biomarkers of respo
2020-06-11

Finally, the identification of predictive biomarkers of response will also allow the more recently discovered CDK inhibitors to be explored in particular genetically-defined contexts, for example by building on recent observations that KRAS mutant tumors are highly sensitive to CDK1 inhibition, and
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Social interaction is known to be the
2020-06-11

Social interaction is known to be the main source of stress in human beings (Dickerson and Kemeny, 2004, Tamashiro et al., 2005). An animal model of social stress should closely mimic real-life situations in human life (Neisewander et al., 2012); in this context, social defeat in an agonistic encoun
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This work aimed to investigate
2020-06-11

This work aimed to investigate whether the increase in liver lipid depots, observed in the fetuses from rats fed a saturated-fat-rich diet, persists later in life in the offspring (a) at 21days of age immediately after weaning and (b) at 140days of age, after healthy nourishing. Furthermore, we want
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Unlike previous studies examining COMT genotyping in healthy
2020-06-11

Unlike previous studies examining COMT genotyping in healthy controls seeking to explain impulsive behaviors, this study sought to examine COMT genotypes in a large sample of individuals with varying levels of gambling behavior to determine whether COMT Caspase-8 Colorimetric Assay Kit was associa
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br Criteria for ER targeted fluorescent probes br
2020-06-11

Criteria for ER-targeted fluorescent probes Survey of fluorescent probes Proposed approach to high affinity fluorescent steroidal ER probes Our proposed approach to the development of a new generation of fluorescent estrogen receptor imaging agents employs many of the elements present in th
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Aliskiren Hemifumarate In a study performed simultaneously b
2020-06-11

In a study performed simultaneously by another group, EWS-FLI-1 introduction into unsorted murine bone marrow-derived Aliskiren Hemifumarate resulted in tumors with various phenotypes including one that is consistent with that of Ewing sarcoma [68]. The tumors expressed markers associated with Ewing
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The eNOS bp VNTR polymorphism
2020-06-11

The eNOS 27-bp VNTR polymorphism has been found to be associated with altered plasma NO levels. This polymorphism also has been associated with many vascular diseases including hypertension, diabetic retinopathy, and diabetic nephropathy in various populations. Notably, our results were different fr
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Regardless of its effect on
2020-06-11

Regardless of its effect on EBV infection, the chemokine system has been found to be regulated in both nasopharyngeal cancer and Hodgkin lymphoma. As such, Hodgkin and Reed–Sternberg (HRS) cells from Hodgkin lymphoma and nasopharyngeal carcinoma cells have been shown to express CXCL8 and CCL17. Furt
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Downregulation of tumor suppressors is a
2020-06-11

Downregulation of tumor suppressors is a major factor that leads to tumorigenesis. Phosphatase and tensin homolog deleted on chromosome 10 (PTEN), a common tumor suppressor, the Cell Counting Kit-8 of which is often downregulated or even absent in the majority of human cancers, functions as a phosph
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