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Phytophthora capsici is a phytopathogenic oomycete a lineage
2020-06-12

Phytophthora capsici is a phytopathogenic oomycete, a lineage of eukaryotic microorganisms in the kingdom Stramenopila, which causes devastating diseases on many economically important vegetables [15]. Hyps are present in the Phytophthora cell wall proteins [16] and phytotoxic elicitor proteins [17]
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Introduction Postoperative delirium POD is
2020-06-12

Introduction Postoperative delirium (POD) is a potentially debilitating disorder experienced by many elderly patients admitted to a surgical intensive care unit (ICU) after noncardiac surgery. Delirium is often defined as acute cognitive dysfunction that is characterized by an altered mental status
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Finally the identification of predictive biomarkers of respo
2020-06-11

Finally, the identification of predictive biomarkers of response will also allow the more recently discovered CDK inhibitors to be explored in particular genetically-defined contexts, for example by building on recent observations that KRAS mutant tumors are highly sensitive to CDK1 inhibition, and
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Social interaction is known to be the
2020-06-11

Social interaction is known to be the main source of stress in human beings (Dickerson and Kemeny, 2004, Tamashiro et al., 2005). An animal model of social stress should closely mimic real-life situations in human life (Neisewander et al., 2012); in this context, social defeat in an agonistic encoun
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This work aimed to investigate
2020-06-11

This work aimed to investigate whether the increase in liver lipid depots, observed in the fetuses from rats fed a saturated-fat-rich diet, persists later in life in the offspring (a) at 21days of age immediately after weaning and (b) at 140days of age, after healthy nourishing. Furthermore, we want
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Unlike previous studies examining COMT genotyping in healthy
2020-06-11

Unlike previous studies examining COMT genotyping in healthy controls seeking to explain impulsive behaviors, this study sought to examine COMT genotypes in a large sample of individuals with varying levels of gambling behavior to determine whether COMT Caspase-8 Colorimetric Assay Kit was associa
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br Criteria for ER targeted fluorescent probes br
2020-06-11

Criteria for ER-targeted fluorescent probes Survey of fluorescent probes Proposed approach to high affinity fluorescent steroidal ER probes Our proposed approach to the development of a new generation of fluorescent estrogen receptor imaging agents employs many of the elements present in th
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Aliskiren Hemifumarate In a study performed simultaneously b
2020-06-11

In a study performed simultaneously by another group, EWS-FLI-1 introduction into unsorted murine bone marrow-derived Aliskiren Hemifumarate resulted in tumors with various phenotypes including one that is consistent with that of Ewing sarcoma [68]. The tumors expressed markers associated with Ewing
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The eNOS bp VNTR polymorphism
2020-06-11

The eNOS 27-bp VNTR polymorphism has been found to be associated with altered plasma NO levels. This polymorphism also has been associated with many vascular diseases including hypertension, diabetic retinopathy, and diabetic nephropathy in various populations. Notably, our results were different fr
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Regardless of its effect on
2020-06-11

Regardless of its effect on EBV infection, the chemokine system has been found to be regulated in both nasopharyngeal cancer and Hodgkin lymphoma. As such, Hodgkin and Reed–Sternberg (HRS) cells from Hodgkin lymphoma and nasopharyngeal carcinoma cells have been shown to express CXCL8 and CCL17. Furt
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Downregulation of tumor suppressors is a
2020-06-11

Downregulation of tumor suppressors is a major factor that leads to tumorigenesis. Phosphatase and tensin homolog deleted on chromosome 10 (PTEN), a common tumor suppressor, the Cell Counting Kit-8 of which is often downregulated or even absent in the majority of human cancers, functions as a phosph
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One of the isolated interactors against Mulan
2020-06-11

One of the isolated interactors against Mulan259–352–Ube2E3 fusion bait was found to be the GABARAP protein, a known member of the Atg8 family that includes LC3 [20]. The Atg8 family-of-proteins are major players in autophagy/mitophagy since they are part of the autophagosome [20], [21], [22]. Our
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br Regulation of p via the ubiquitin
2020-06-11

Regulation of p53 via the ubiquitin-proteasome pathway Studies into regulation of p53 via PTM processes that involve phosphorylation, acetylation, ubiquitination, SUMOylation, neddylation, and methylation are being increasingly reported [23], [24]. Phosphorylation and acetylation of p53 stimulate
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Introduction Mycobacterium leprae the causative agent
2020-06-11

Introduction Mycobacterium leprae, the causative agent of leprosy, affects skin, peripheral nerves and upper respiratory tract [1]. Although leprosy has been eradicated from most of the countries, it still affects approximately a quarter of a million people from India [2]. Details of many bacteriol
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The outcome of DGK function will thus depend on the
2020-06-11

The outcome of DGK function will thus depend on the binding partners of each DGK isoform, and the effects that they exert can be quite different. A clear example of this concept has been demonstrated for the type IV DGKs, ζ and ι, which are structurally very similar but have opposing effects on Ras
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